Our polyamine-based ingredient is vegan, derived from amino acids and promotes beauty from within and healthy aging. Polyamines, such as spermidine, are naturally occurring compounds found in breast milk, beans and mushrooms. These polyamines are known for their various health benefits, including cellular rejuvenation, antioxidant activity, and support for healthy aging.

The key mechanism of action behind polyamines like spermidine is autophagy, the process by which cells remove damaged components and recycle them. This cellular regeneration process is essential for maintaining optimal health and preventing the accumulation of "zombie" cells that can cause damage over time.

By mimicking the effects of intermittent fasting, spermidine can promote autophagy and support various health benefits, including brain health, DNA stability, mitochondrial health, and even hair growth. The high antioxidant activity of polyamines contributes to reducing oxidative stress and promoting the formation of younger, healthier cells.

Is calm (beauty) JUST WHEAT GERM?

No. Ours is derived from amino acids and is GRAS-certified and vegan, making it a safe and cost-effective alternative to obtaining polyamines like spermidine compared to sourcing them from wheat germ. The high cost associated with extracting spermidine from wheat germ at significant concentrations makes it commercially unviable for mass production, which is where calm (beauty) shines. 

Be cautious of suppliers claiming to offer spermidine derived from wheat germ at any desired concentration, as this could indicate a synthetic blend of spermidine with wheat germ rather than a pure form of the compound.

While the exact mechanisms of action of spermidine and polyamines are still being researched, existing scientific literature reports that spermidine plays a role in supporting cellular health and longevity. There is also emerging evidence indicating spermidine's potential benefits for brain health, normal hair growth, and modulation of inflammation markers.

As with any health supplement or product, it is essential to consider the source, purity, and effectiveness of the ingredients. Consumers should always conduct thorough research and consult with healthcare professionals before incorporating new supplements into their routine to ensure safety and efficacy.

Here's how calm (beauty) spermidine works:

Our spermidine plays a significant role in supporting various aspects of health and longevity, although the exact mechanisms of action are not fully understood. Scientific literature indicates that spermidine supports cellular health and longevity, with emerging evidence pointing to its broader benefits for brain health, normal hair growth, and modulation of inflammation markers.

Here are some key functions that polyamines like spermidine are believed to support based on current research:

1. Plays multiple roles in health span: Spermidine's antioxidant and anti-inflammatory effects contribute to overall health and well-being.

2. Supports mitochondrial health: Spermidine is thought to play a role in maintaining the health and function of mitochondria, which are essential for energy production in cells.

3. Supports autophagy: Spermidine may help promote autophagy, the cellular process of recycling and removing damaged components to maintain cellular health.

4. Supports apoptosis: Spermidine may also play a role in regulating apoptosis, the programmed cell death process that is crucial for maintaining tissue homeostasis.

5. Supports DNA stability: Spermidine is believed to help maintain DNA stability, which is essential for proper cellular function and replication.

6. Data suggest exogenous spermidine supplementation supports lifespan and longevity: Some studies suggest that supplementing with spermidine may have beneficial effects on lifespan and longevity, although more research is needed to fully understand these effects.

SPERMIDINE and a healthy inflammatory response

Chronic inflammation can lead to premature aging and have negative effects on immune health. In addition to autophagy, another of spermidine’s mechanisms is influencing inflammatory pathways. Spermidine has been shown to decrease the inflammatory cytokine TNF-α, which may support Yuth’s role in maintaining a healthy inflammatory response. The end effect may support less premature aging.

SPERMIDINE and cognitive health

In a 2021 study by Schroeder et al, researchers evaluated the possible correlation of spermidine intake with cognitive function and decline in humans. The analysis lent “strong support to the concept that nutrition rich in spermidine (SPD) protects against cognitive impairment and decline.” Improving one’s diet and/or taking a spermidine supplement is crucial to maintaining cognitive health as we age. You can find spermidine (as Yüth™) by contacting us today.

***THESE STATEMENTS HAVE NOT BEEN APPROVED OR REGULATED BY THE FDA. WE ARE NOT DOCTORS, SO MAKE SURE YOU ARE RESPONSIBLE FOR RESEARCHING FURTHER IF YOU ARE INTERESTED IN THIS SUBJECT***